| # | Word | Igbo Meaning | English Meaning |
| 1 | Oak | Osisi akwụkwọ ya na-agbụcha agbụcha site n'afọ ruo n'afọ. | Decidous forest tree |
| 2 | Oasis | Ala na-emeta nri dị nọzara. | Fertile spot in desert. |
| 3 | Oat | ụ mkpụrụ osisi. | Grain of cereal plant. |
| 4 | Oath | Ịṅụ iyi. | Confirmation of truth of statement by naming of something sacred |
| 5 | Obdurate | Adịghị erube isi. | Stubborn, unyielding. |
| 6 | Obedience | Ịkpọ isi ala; nrube isi | A bow |
| 7 | Obese | Buru oke ibu. | Very fat |
| 8 | Obey | Rube isi. | Do as ordered |
| 9 | Obfuscate | Teji oji, gbaji. | Darken |
| 10 | Obiter | Na mberede | Accidentally |
| 11 | Obituary | Ọkwa ọnwụ | Notice of death |
| 12 | Object | Ihe. | Material thing |
| 13 | Objection | Gbagha. | State in opposition |
| 14 | Objective | Ebu m n'uche. | Thing or place aimed at |
| 15 | Objure | Ba mba | Reprove; scold |
| 16 | Oblation | Onyinye | Offering |
| 17 | Oblige | Aghaghị ime n'ihe mmụọ ma ọ bụ iwu. | Bind morally or legally to do service to. |
| 18 | Oblique | Akwụghị ọtọ. | Slanting |
| 19 | Obliterate | Hichapụ | Blot out |
| 20 | Oblivion | Ichefu | Forgetting or being forgotten |